A new recombinant strain of HIV-1 discovered in Cyprus | NEWS.am Medicine
The discovery of a new recombinant strain of HIV-1 in Cyprus was recently announced, under the name “CRF91_cpx”, by scientists from the University of Cyprus and the National HIV Laboratory in Los Alamos, New Mexico in the United States. -United.
According to an announcement from the University of Cyprus, molecular research on HIV-1 has been carried out at the University of Cyprus in collaboration with the Gregorios AIDS Clinic at Larnaca General Hospital, leading to the discovery of a new Recombinant HIV (chimera) 1 strain, consisting of four strains of HIV-1: CRF02_AG, G, J and U (U refers to an unknown subtype, which does not belong to any established subtype). This new recombinant strain of HIV-1 has been classified as a new circulating recombinant form of HIV-1 and designated “CRF91_cpx” by the Los Alamos National Laboratory (USA) HIV database. The results of this discovery, he adds, were published on August 18, 2022 by the prestigious international medical journal Virulence.
“The question is, ‘was it created in Cyprus or was it imported to Cyprus’? The answer is that we don’t know at the moment”, -Dr. Kostrikis
CRF91_cpx was discovered among 16 people living with HIV-1 in Cyprus, 14 whose samples were used for the study and two discovered after the study was published. “Currently, epidemiological analyzes demonstrate that CRF91_cpx is circulating primarily among Cypriot men who have sex with men (MSM) who became infected in Cyprus,” the university statement read. After the initial discovery, he adds, ongoing phylogenetic analyzes conducted with HIV-1 genomes isolated from newly diagnosed patients in Cyprus have identified two additional Cypriot MSM infected with the CRF91_cpx strain. “Collectively, the data suggests ongoing transmission of this novel recombinant strain of HIV-1, CRF91_cpx, in Cyprus with currently unknown clinical manifestations,” he said.